Abstrak
The COVID-19 outbreak that began in December 2019 in Wuhan, China has become a pandemic. The whole world is struggling to fight against COVID-19, every effort has been made. In addition, this disease also has various risk factors in the form of characteristics and comorbidities of the disease. The study aimed to examine the relationship between smoking and comorbidities with COVID-19 mortality using a systematic review and meta-analysis. ,13-1,22). Comorbid diabetes mellitus had a significant relationship with mortality with a p-value of 0.00001 (OR 2.45 95% CI 1.55-3.88). Hypertension has a significant relationship with mortality with a p-value of 0.0001 (OR 3.88 95% CI 0.92-16.44). Cardiovascular has a significant relationship with mortality with a p-value of 0.005 (OR 3.77 95% CI 1.51-9.43). COPD has a significant relationship with mortality with a p-value of 0.00001 (OR 4.68 95% CI 3.11-7.04). Factors for mortality risk factors for smoking, diabetes mellitus, hypertension, cardiovascular and COPD have a significant relationship and can increase the risk of death in patients with COVID-19
Referensi
Rothan HA, Byrareddy SN. The epidemiology and pathogenesis of coronavirus disease (COVID-19) outbreak. J Autoimmun [Internet]. 2020;109(March):102433. Available from: https://doi.org/10.1016/j.jaut.2020.102433
WHO. Responding to community spread of COVID-19. Interim Guid [Internet]. 2020;(March):1–6. Available from: https://www.who.int/publications/i/item/responding-to-community-spread-of-covid-19
Kemenkes RI. Kementerian Kesehatan Republik Indonesia [Internet]. [cited 2021 Nov 14]. Available from: https://www.kemkes.go.id/article/print/20101400002/13-2-persen-pasien-covid-19-yang-meninggal-memiliki-penyakit-hipertensi.html
WHO. COVID-19 Weekly Epidemiological Update. 2021;(November).
Cai H. Sex difference and smoking predisposition in patients with COVID-19. Lancet Respir Med [Internet]. 2020;8(4):e20. Available from: http://dx.doi.org/10.1016/S2213-2600(20)30117-X
Lei Fang, George Karakiulakis *Michael Roth. Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? The. Lancet Respir Med. 2019;8(4):e21.
Stroup DF, Berlin JA, Morton SC, Olkin I, Williamson G, Moher D, et al. Meta-analysis of Observational Studies in Epidemiology: A Proposal for Reporting - Meta-analysis Of Observational Studies in Epidemiology (MOOSE) Group B. JAMA Neurol. 2000;283:2008–12.
Prats-uribe A, Prieto-alhambra D, Petersen I. Smoking and COVID-19 Infection and Related Mortality : A Prospective Cohort Analysis of UK Biobank Data. 2021;(April).
Salah HM, Sharma T, Mehta J. Smoking Doubles the Mortality Risk in COVID-19 : A Meta-Analysis of Recent Reports and Potential Mechanisms. 2020;12(10).
Berlin I, Thomas D, Faou A Le, Cornuz J. COVID-19 and Smoking. 2020;1–3.
Karanasos A, Aznaouridis K. Impact of Smoking Status on Disease Severity and Mortality of Hospitalized Patients With COVID-19 Infection : A Systematic Review and. 2020;(1):1657–9.
Mondi A, Lorenzini P, Castilletti C, Gagliardini R, Lalle E, Corpolongo A, et al. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID- 19 . The COVID-19 resource centre is hosted on Elsevier Connect , the company ’ s public news and information . 2020;(January).
Petersen F, Yu X. Association of Cigarette Smoking , COPD , and Lung Cancer With Expression of SARS-CoV-2 Entry Genes in Human Airway Epithelial. 2020;7(March):1–10.
Huang I, Lim MA, Pranata R. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID- 19 . The COVID-19 resource centre is hosted on Elsevier Connect , the company ’ s public news and information . 2020;(January).
Pititto BDA, Dualib PM, Zajdenverg L, Dantas JR. Severity and mortality of COVID 19 in patients with diabetes , hypertension and cardiovascular disease : a meta ‑ analysis. Diabetol Metab Syndr [Internet]. 2020;4:1–12. Available from: https://doi.org/10.1186/s13098-020-00586-4
Lestari N, Ichsan B, Kedokteran F, Surakarta UM, Lestari KN, Alamat MPH. Diabetes Melitus Sebagai Faktor Risiko Keparahan Dan Kematian Pasien Covid-19 : Meta-Analisis Diabetes Mellitus As a Risk Factor for Severity and Mortality of Covid-19 : a Meta-Analysis. Biomedika. 2020;13(1):83–94.
Bae JH. COVID-19 and diabetes mellitus: from pathophysiology to clinical management. Nat Rev Endocrinol [Internet]. 2021;17(January). Available from: http://dx.doi.org/10.1038/s41574-020-00435-4
Ahmad Alkautsar. HUBUNGAN PENYAKIT KOMORBID DENGAN TINGKAT KEPARAHAN PASIEN COVID-19. J Med Hutama. 2021;03(01):1488–94.
Mishra P, Parveen R, Bajpai R, Samim M, Agarwal NB. Impact of cardiovascular diseases on severity of COVID-19 patients : A systematic review. 2021;50(1):52–60.
Sayer G, Griffin JM. COVID-19 and Cardiovascular Disease. 2020;2019:1648–55.
Oudit GY, Kassiri Z, Jiang C, Liu PP, Poutanen SM, Penninger JM, et al. SHORT REPORT SARS-coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS. 2009;39:618–25.
Rabbani G, Mohammad S, Islam S, Aziz M, Amin N, Marzan B, et al. Expert Review of Respiratory Medicine Pre-existing COPD is associated with an increased risk of mortality and severity in COVID-19 : a rapid systematic review and meta-analysis. Expert Rev Respir Med [Internet]. 2021;15(5):705–16. Available from: https://doi.org/10.1080/17476348.2021.1866547
Gerayeli F V, Milne S, Cheung C, Li X, Wei C, Yang T, et al. EClinicalMedicine COPD and the risk of poor outcomes in COVID-19 : A systematic review and meta-analysis. EClinicalMedicine [Internet]. 2021;33:100789. Available from: https://doi.org/10.1016/j.eclinm.2021.100789
Alqahtani FY, Aleanizy FS, El RA, Mohamed H, Alanazi MS, Mohamed N, et al. Prevalence of comorbidities in cases of Middle East respiratory syndrome coronavirus : a retrospective study. 2019;
Team CDCC-19 R, Team CDCC-19 R, Team CDCC-19 R, Chow N, Fleming-Dutra K, Gierke R, et al. Preliminary estimates of the prevalence of selected underlying health conditions among patients with coronavirus disease 2019—United States, February 12–March 28, 2020. Morb Mortal Wkly Rep. 2020;69(13):382–6.
Ebuy H, Gessesse Z, Gebrecherkos T, Kebede Y, Weldegebreal A, Hagazi M, et al. International Journal of Infectious Diseases Clinical features and risk factors associated with morbidity and mortality among patients with COVID-19 in northern Ethiopia. Int J Infect Dis [Internet]. 2021;105:776–83. Available from: https://doi.org/10.1016/j.ijid.2021.03.037
Castro MC, Gurzenda S, Macário EM, França GVA. Characteristics, outcomes and risk factors for mortality of 522 167 patients hospitalised with COVID-19 in Brazil: a retrospective cohort study. BMJ Open. 2021 May;11(5):e049089.
Ishtiaq R, Patti DK, Kumar A, Sandho G, Jacob K, Luthra K, et al. Clinical characteristics and outcomes of patients with Corona Virus Disease 2019 ( COVID-19 ) at Mercy Health Hospitals , Toledo , Ohio. 2021;2019:1–11. Available from: http://dx.doi.org/10.1371/journal.pone.0250400
Rika J, Id M, Nyembu RK, Telo GM, Ngoy D, Sakobo TM, et al. PLOS ONE Clinical characteristics of COVID-19 patients hospitalized at Clinique Ngaliema , a public hospital in Kinshasa , in the Democratic Republic of Congo : A retrospective cohort study. 2020;1–15. Available from: http://dx.doi.org/10.1371/journal.pone.0244272
Puebla D, Watts A, Seashore J, Polychronopoulou E. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID- 19 . The COVID-19 resource centre is hosted on Elsevier Connect , the company ’ s public news and information . 2020;(January).
Id AP, Gillani FS, Shi Y, Hardesty A, Mccarthy M, Aridi J, et al. Predictors of severity and mortality among patients hospitalized with COVID-19 in Rhode Island. 2021;1–15. Available from: http://dx.doi.org/10.1371/journal.pone.0252411
Almazeedi S, Al-youha S, Jamal MH, Al-haddad M, Al-muhaini A, Al-ghimlas F, et al. EClinicalMedicine Characteristics , risk factors and outcomes among the fi rst consecutive 1096 patients diagnosed with COVID-19 in Kuwait. EClinicalMedicine [Internet]. 2020;24:100448. Available from: https://doi.org/10.1016/j.eclinm.2020.100448
Martins-Filho PR, Antunes de Souza Araújo A, Pereira LX, Quintans-Júnior LJ, de Souza Barboza W, Cavalcante TF, et al. Factors Associated with Mortality among Hospitalized Patients with COVID-19: A Retrospective Cohort Study. Am J Trop Med Hyg. 2021 Jan;104(1):103–5.
Caliskan T, Saylan B. Smoking and comorbidities are associated with COVID-19 severity and mortality in 565 patients treated in Turkey: a retrospective observational study. Rev Assoc Med Bras. 2020 Dec;66(12):1679–84.
Lee S-G, Park GU, Moon YR, Sung K. Clinical Characteristics and Risk Factors for Fatality and Severity in Patients with Coronavirus Disease in Korea: A Nationwide Population-Based Retrospective Study Using the Korean Health Insurance Review and Assessment Service (HIRA) Database. Int J Environ Res Public Health. 2020 Nov;17(22).
Timberlake DT, Narayanan D, Ogbogu PU, Raveendran R. Severity of COVID-19 in hospitalized patients with and without atopic disease. World Allergy Organ J [Internet]. 2021;14(2):100508. Available from: https://doi.org/10.1016/j.waojou.2021.100508
Liu K, Mubarik S, Shi F, Wen H, Zeng Z. Epidemiological characteristics of patients with severe COVID-19 infection in Wuhan, China: evidence from a retrospective observa- tional study. 2020;1940–50.
Jaspard M, Saliou M, Juchet S, Dienderé E, Serra B, Kojan R, et al. International Journal of Infectious Diseases Clinical presentation , outcomes and factors associated with mortality : A prospective study from three COVID-19 referral care centres in West Africa. 2021;108:45–52.
Parra-Bracamonte GM, Lopez-Villalobos N, Parra-Bracamonte FE. Clinical characteristics and risk factors for mortality of patients with COVID-19 in a large data set from Mexico. Ann Epidemiol. 2020;52(January):93-98.e2.
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