Abstrak
Coronavirus Disease 19 (COVID-19) merupakan penyakit mematikan yang dapat membunuh ribuan orang di dunia. Namun, tidak banyak peneliti yang menyadari bahwa kandungan NO dapat membunuh virus COVID-19. Metode penelitian ini adalah desain penelitian menggunakan metode retrospektif, prospektif dan tinjauan sistematis. Pencarian sumber referensi dimulai pada 10 Maret - 01 Juni 2021, menggunakan beberapa database online: 1) Pubmed, 2) Science Direct, 3) Google Scholar. Kata kunci yang digunakan dalam pencarian istilah: COVID-19, novel Coronavirus, SARS-CoV-2, nitric oxide (NO), coklat hitam, macrophages dan termasuk dalam jurnal yang terakreditasi. Penelitian ini mencari daftar referensi dari penelitian yang meliputi 103 penelitian yang diambil melalui pencarian. Sebanyak 63 pasal dalam pembersihan, dan ada 8 pasal yang masuk dalam pembahasan. Hasil tinjauan ini memberikan bukti bahwa COVID-19 dapat dilemahkan dan dimatikan oleh kandungan NO yang dihasilkan oleh makrofag dan disuplai dengan konten NO yang dimodulasi oleh coklat hitam. modulasi makanan kaya NO seperti coklat hitam dapat efektif dengan efek protektifnya sebagai bentuk pencegahan dari paparan COVID-19. NO juga dapat menyembuhkan beberapa penyakit seperti tekanan darah tinggi, diabetes, penyakit kardiovaskular dan beberapa infeksi saluran pernapasan.
Referensi
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