Abstrak
Pengaruh konsumsi diet dengan kanker kolorectal masih kontroversial. Penelitian dengan studi systematic review dan meta analisis dapat membuktikan kebenarannya. Penelitian ini bertujuan untuk mengetahui pengaruh konsumsi serat dengan pengurangan risiko kanker kolon di negara barat. Penelitian ini menggunakan studi meta-analisis berdasarkan artikel penelitian tentang konsumsi serat mengurangi risiko kanker kolorektal di negara-negara barat yang diterbitkan antara Januari 2000 dan Januari 2019 di database artikel online PubMed, ProQuest dan EBSCO. Odds rasio gabungan (POR) dihitung dengan fixed-effect model atau random effect model. Data disajikan dalam bentuk forest plots. Data dianalisis dengan menggunakan software Stata versi 14.2 (Stata Corporation). Penelitian ini mereview 405 artikel. Ada 7 penelitian yang dilakukan telaah sistematis dan dilanjutkan dengan Meta-analisis. Hasilnya menunjukkan konsumsi serat mengurangi risiko kanker kolorektal di negara-negara barat (RR = 0,83 [95% CI 0,75-0,93]). Hasil penelitian ini menyimpulkan konsumsi serat dapat mengurangi risiko kanker kolorektal di negara barat.
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